View & Download CD data for CD0003672000

Beta-crystallin B2 (beta-b2 crystallin)


Citation: P. Evans, O.A. Bateman, C. Slingsby, B.A. Wallace 2007 Experimental Eye Research 84 1001-1008


Citation: The PCDDB (protein circular dichroism data bank): A bioinformatics resource for protein characterisations and methods development.
Ramalli SG, Miles AJ, Janes RW, Wallace BA., J Mol Biol (2022)


CSA/ACS Standard Spectrum Millidegrees (theta) Download
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Raw Sample Spectra Millidegrees (theta) Download
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Raw Sample Spectra 2 Millidegrees (theta) Download
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Raw Baseline Spectra Millidegrees (theta) Download
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Raw Baseline Spectra 2 Millidegrees (theta) Download
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Raw Baseline Spectra 3 Millidegrees (theta) Download
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Average Sample Millidegrees (theta) Download
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Averaged Baseline Millidegrees (theta) Download
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HT / High Voltage / Dynode Spectra HT/Dynode Units Download
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HT / High Voltage / Dynode Spectra 2 HT/Dynode Units Download
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Net Smoothed Spectrum Millidegrees (theta) Download
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Final Processed Spectrum Delta Epsilon Download
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Validation report compiled by Validichro v1.2.5, 2012-08-15, 4:10pm. - PASS

At a glance
Downloads 1559
Depositor Andrew Miles
Uniprot P62697
Alpha Fold
PDB 1bd7
EC -
CATH Class 2.60.20.10
Protein Type soluble globular

Sample

Protein Name Beta-crystallin B2 ?
Alternative Protein Names Beta-B2 crystallin ?
Source Organism Rattus Norvegicus ?
Protein Supplier C. Slingsby, Birkbeck ?
Expression System or natural source Natural source ?
Expressed As Wild-type ?
Mutation Details No data provided ?
Expression tags (if any) No data provided ?
Ligands Present and Concentration or ratio No data provided ?
Macromolecular Partner(s) and Concentration or ratio No data provided ?
Deposition Date 2012-08-20 ?

Experiment

CD or SRCD SRCD ?
Protein Concentration (mg/ml) 2.70 ?
Concentration Quantification Method QAA ?
Protein Purity (%) No data provided ?
Purity Quantification Method No data provided ?
Buffer Contents and Concentrations 10mM phosphate pH7.0 ?
Baseline Contents 10mM phosphate pH 7.0 ?
Experimental Temperature (C) 4 ?
Instrument or beamline ISA UV1 ?
Detector Angle (Scattering Angle) No data provided ?
Sample Cell Pathlength (cm) 0.005 ?
Cell Pathlength Calibration Method Interferometry ?
Sample Cell Type Cylindrical-Demountable ?
Sample Cell Composition Suprasil ?
Sample Chamber Atmosphere Nitrogen ?
Number of repeat scans 3 ?
Continuous or Stepped scan Stepped ?
Maximum (highest) wavelength, nm 300 ?
Minimum (lowest) wavelength, nm 175 ?
Criteria for low wavelength cutoff HT value ?
Wavelength interval, nm 1 ?
Dwell or Averaging time, seconds 2 ?
Experimental Collection date 2004-05-11 ?
Local Spectrum Identifier a6354 ?

Calibration

CSA or ACS CSA ?
Dichroism Units for CSA Standard Millidegrees (theta) ?
Final Spectrum Calibrated YES ?
CSA/ACS Standard Concentration (mg/ml) 9.71 ?
CSA/ACS Pathlength (mm) 0.10 ?
CSA/ACS Zeroed at - ?
CSA/ACS Date Measured 2004-05-11 ?
CSA/ACS Ratio (192.5nm and 290.0 nm) 1.91 ?
CD signal at 290nm (mdeg) 27.8 ?
CSA/ACS Experiment temperature, C 25 ?

Data process.

Molecular Weight 23249.7 ?
Number of Residues 204 ?
Mean Residue Weight 114.5 ?
Data Processing Software Name CDTool ?
Data Processing Software Version 1.4 ?
Wavelength Range for Zeroing 263-270 ?
Number of Smoothing Points 7 ?

Sec. struct.

Secondary Structure Calculated from Crystal structure ?
DSSP value: alpha helix 0.000 ?
DSSP value: 3-10 helix 0.100 ?
DSSP value: pi helix 0.000 ?
DSSP value: beta strand 0.431 ?
DSSP value: beta bridge 0.011 ?
DSSP value: bonded turn 0.063 ?
DSSP value: bend 0.091 ?
DSSP value: loop or irregular 0.303 ?

Tertiary

PDB ID 1bd7 ?
UniProt ID P62697 ?
Enzyme Classification (EC) - ?
Medline Entry 17400211 ?
Cath Classification 2.60.20.10 ?
Sequence ASDHQTQAGK PQPLNPKIII FEQENFQGHS HELSGPCPNL KETGMEKAGS VLVQAGPWVG YEQANCKGEQ FVFEKGEYPR WDSWTSSRRT DSLSSLRPIK VDSQEHKIIL YENPNFTGKK MEIVDDDVPS FHAHGYQEKV SSVRVQSGTW VGYQYPGYRG LQYLLEKGDY KDNSDFGAPH PQVQSVRRIR DMQWHQRGAF HPSS ?
Type of protein soluble globular ?
Keyword/phrase A No data provided ?
Keyword/phrase B No data provided ?
Keyword/phrase C No data provided ?
Keyword/phrase D No data provided ?
Keyword/phrase E No data provided ?
Keyword/phrase F No data provided ?
Keyword/phrase G No data provided ?
Keyword/phrase H No data provided ?
Keyword/phrase I No data provided ?
Keyword/phrase J No data provided ?
Publication Authors P. Evans, O.A. Bateman, C. Slingsby, B.A. Wallace ?
Publication Year 2007 ?
Publication Journal Experimental Eye Research ?
Publication Title A reference dataset for circular dichroism spectroscopy tailored for the b-gamma-crystallin lens proteins ?
Publication Volume 84 ?
Publication Pages 1001-1008 ?

Depositor

Depositor Name Andrew Miles ?
Department/School name crystallography ?
University/Institution/Corporation Birkbeck ?
Depositor Country United Kingdom ?
Name of Principal Investigator (if not depositor) B.A.Wallace ?

Validation report compiled by Validichro v1.2.5, 2012-08-15, 4:10pm. - PASS

Depositors Notes:

Missing Wavelengths PASS ?
Maximum Delta Epsilon PASS ?
Minimal Level of Maximum Delta Epsilon PASS ?
Peak Locations PASS ?
Feature Width PASS ?
Experimental Temperature PASS ?
UniProt sequence PASS ?
Molecular Weight PASS ?
Number of Residues PASS ?
Mean Residue Weight value PASS ?
Concentration and Pathlength PASS ?
CSA / ACS peak ratio PASS ?
CSA / ACS Temperature PASS ?
Peak Shift test PASS ?
Standard Deviation PASS ?
Noise: 260-270nm PASS ?
Flat topped peaks PASS ?
Wavelength range PASS ?
Interval resolution PASS ?
High Tension Voltage 240-260nm PASS ?
Projection Test PASS ?
Standard Deviation At Peak PASS ?
Depositor Note ?

The PCDDB is a development of the Department of Biological Sciences, Institute of Structural and Molecular Biology, Birkbeck College, University of London and the School of Biological and Chemical Sciences, Queen Mary University of London, UK. It is supported by a grant from the BBSRC. Copyright of the design and implementation of this site are retained by the schools and the authors.