Welcome to the PCDDB - a public repository for circular dichroism spectral data

The Protein Circular Dichroism Data Bank (PCDDB) is a public repository that archives and freely distributes circular dichroism (CD) and synchrotron radiation CD (SRCD) spectral data and their associated experimental metadata.

All entries undergo validation and curation procedures to ensure completeness, consistency and quality of the data included. A web-based interface enables users to browse and query sample types, sample conditions, experimental parameters and provides spectra in both graphical display format and as downloadable text files.

The entries are linked, when appropriate, to primary sequence (UniProt) and structural (PDB) databases, as well as to secondary databases such as the Enzyme Commission functional classification database and the CATH fold classification database, as well as to literature citations.

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Citing the PCDDB

A condition of use of the data in this website is that any publication or presentation using any data from the PCDDB must cite both the original reference that created the data (noted in the individual records) plus the pcddb reference:

Whitmore, L., Miles, A.J., Mavridis, L., Janes, R.W. and Wallace, B.A.,
PCDDB: new developments at the Protein Circular Dichroism Data Bank.
Nucleic Acids Research (2017) 45 (D1): D303-D307 .

Whitmore L, Mavridis L, Wallace BA, Janes RW
DichroMatch at the protein circular dichroism data bank (DM@PCDDB): A web-based tool for identifying protein nearest neighbors using circular dichroism spectroscopy
Protein Sci. 2018 Jan

Current holdings

Released entries: 611

Entries in pre-release: 385

The PCDDB is a development of the Department of Crystallography, Institute of Structural and Molecular Biology, Birkbeck College, University of London and the School of Biological and Chemical Sciences, Queen Mary University of London, UK. It is supported by a grant from the BBSRC. Copyright of the design and implementation of this site are retained by the Schools and the authors. © 2006-2020